Whole genome sequencing of bacterial genomes - tools and applications

This comprehensive course delves into the applications of Whole Genome Sequencing (WGS) for bacterial genomes, crucial in the medical sector. Through a series of modules, participants will gain an in-depth understanding of WGS technology and its applications, including species identification, antimicrobial resistance surveillance, and plasmid characterization.

• Gain insight into principles of bacterial typing and WGS applications in surveillance
• Learn about Next-Generation Sequencing (NGS) and de novo assembly of raw reads
• Explore tools for species identification, MLST typing, and resistance gene detection
• Understand Salmonella and E. coli typing, plasmid replicon detection, and phylogenetic analysis
• Utilize genomic tools for batch analysis and typing of genomic data
• Develop skills in constructing phylogenetic trees and creating sequence databases

This course, offered by Technical University of Denmark (DTU), provides a valuable opportunity to acquire practical knowledge in using online tools for WGS analysis and exercises for real-case scenarios. Upon completion, participants will be equipped to apply WGS technology and bioinformatic tools effectively for the surveillance and characterization of bacterial genomes.