Course

Experimental Methods in Systems Biology

Icahn School of Medicine at Mount Sinai

Explore the technologies driving systems biology experimentation in the "Experimental Methods in Systems Biology" course. Delve into RNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging, gaining insight into how cells respond to perturbations. This comprehensive program provides a broad overview of experimental techniques crucial for obtaining quantitative data needed for computational modeling in systems biology. From theoretical foundations to real wet lab environments, you'll gain practical knowledge on performing these techniques and analyzing resulting data for quality and content.

  • Gain insight into the technologies underlying experimentation in systems biology
  • Learn about RNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging
  • Understand how cells respond to experimental perturbations
  • Obtain practical knowledge on performing experimental techniques and analyzing resulting data

Certificate Available ✔

Get Started / More Info
Experimental Methods in Systems Biology
Course Modules

Embark on a comprehensive journey through eight modules to explore cutting-edge experimental methods in systems biology. Dive into RNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging, gaining practical knowledge and skills for computational modeling.

Introduction

MODULE 1: Introduction

  • Gain a comprehensive scope and overview of the course
  • Learn about biological model systems and experimental perturbations
  • Understand the measurement of nucleic acids and protein states
  • Participate in quizzes to test your understanding

Deep mRNA Sequencing

MODULE 2: Deep mRNA Sequencing

  • Explore the history of sequencing and the advancements in 2nd and 3rd generation sequencing
  • Learn about Illumina-based mRNA sequencing and its data analysis
  • Watch lab-based videos for practical insights

Mass Spectrometry-Based Proteomics

MODULE 3: Mass Spectrometry-Based Proteomics

  • Understand the basics of mass spectrometry and its quantification in proteomics
  • Participate in lab-based videos for hands-on experience and data analysis
  • Engage in a quiz to assess your knowledge

Midterm Exam

MODULE 4: Midterm Exam

Assessment module for evaluating your understanding of the course material.

Flow and Mass Cytometry for Single Cell Protein Levels and Cell Fate

MODULE 5: Flow and Mass Cytometry for Single Cell Protein Levels and Cell Fate

  • Learn about flow cytometry, mass cytometry, and cytometry data analysis
  • Participate in lab-based videos for practical insights
  • Engage in a quiz to test your knowledge

Live-cell Imaging for Single Cell Protein Dynamics

MODULE 6: Live-cell Imaging for Single Cell Protein Dynamics

  • Explore fluorescence microscopy and the visualization of molecules in living cells
  • Learn about quantification and watch lab-based videos for practical understanding
  • Participate in a quiz to assess your knowledge

Integrating and Interpreting Datasets with Network Models and Dynamical Models

MODULE 7: Integrating and Interpreting Datasets with Network Models and Dynamical Models

  • Understand omics data and network model analyses
  • Learn about dynamical model analyses and engage in a case study
  • Participate in a quiz to test your understanding

Final Exam

MODULE 8: Final Exam

Assessment module for evaluating your understanding of the course material.

More Research Courses

Drug Development

University of California San Diego

This course on Drug Development offers insights from industry experts and faculty at the University of California San Diego. Gain knowledge about clinical trial...

MRI Fundamentals

Korea Advanced Institute of Science and Technology(KAIST)

MRI Fundamentals is a comprehensive course covering the basic principles of magnetic resonance imaging (MRI). Learners will gain expertise in MRI physics, data acquisition...

Operational Research for Humanitarians

University of Geneva

Operational Research for Humanitarians is a comprehensive course that equips humanitarian professionals and junior researchers with essential knowledge and skills...

Whole genome sequencing of bacterial genomes - tools and applications

Technical University of Denmark (DTU)

Whole genome sequencing of bacterial genomes - tools and applications. Learn to apply WGS technology and bioinformatic tools for surveillance and characterization...